IL-12 family members in experimental colitis
نویسندگان
چکیده
منابع مشابه
Cutting edge: IL-23 cross-regulates IL-12 production in T cell-dependent experimental colitis.
Although IL-12 and IL-23 share the common p40 subunit, IL-23, rather than IL-12, seems to drive the pathogenesis of experimental autoimmune encephalomyelitis and arthritis, because IL-23/p19 knockout mice are protected from disease. In contrast, we describe in this study that newly created LacZ knockin mice deficient for IL-23 p19 were highly susceptible for the development of experimental T ce...
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ژورنال
عنوان ژورنال: Mucosal Immunology
سال: 2008
ISSN: 1933-0219,1935-3456
DOI: 10.1038/mi.2008.45